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Hypersensitivity to naproxen or to any of the excipients.
Naproxen is contraindicated in patients who have previously shown hypersensitivity reactions (e.g. nasal polyps, asthma, rhinitis, angioedema or urticaria) in response to ibuprofen, aspirin or other non-steroidal anti-inflammatory/analgesic drugs. These reactions have the potential of being fatal. Severe anaphylactic-like reactions to naproxen have been reported in such patients.
Severe heart failure, hepatic failure or renal failure.
During the last trimester of pregnancy.
History of upper gastrointestinal bleeding or perforation, related to previous NSAIDs therapy.
